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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16765355ae82290044a400745d7a9751671800e4216157958ae554de438dae9' 
  AND token = '78116LuErqgR7G44uM2MRsXU37fzzKoWhUn+l90uOTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}