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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7aead84bd2a292e6dbfe82cb4a3726481ff15952b3865f06f29f3436aeeda79' 
  AND token = 'qu+iB/lTBmn2gfAhQimAjXr7BeDoZQSpvNZ+Wnren+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}