SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918d388f9c5d7755b6af49570d9b2b8b30b777bb53d51bcd1edbe09eb6390f87' 
  AND token = 'w2EijnfRVmMjBfO1p42a8qaAPSZISyI/zuAwlIV4G5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}