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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6439a49e2a2c1865e35f66228382025257cf842acdb00f821969a8a5c05141b6' 
  AND token = 'n/aFGCPCn4+wxv3DnEfFZwMkJnP/enWOQ599UH0N2ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}