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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffa0b5e3395efd250789eca7573927d1f4cb39d1894fef3dda144b44eab7fed5' 
  AND token = 'VAwR0XksPR8QidOTKPLSEm4FrokyRDSa/fvPWkm+pNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}