SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562569ecaee37fe3efbce6f88fc1a5d9378b7f7bb3251a7df0edcd295dd915ca' 
  AND token = '4xwBYRAqTE0R1Vmj3BVZvBiSSObmpx97EtZKtKZDqhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}