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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33872f5de767a5c207303340567b7fa2a5e52de55500bf7dd79dd29e946a9275' 
  AND token = 'fHQcO2V1vMf+JOBEkNETNcHs7RSqL9/f/rhRxX6F5iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}