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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf7fefe1476bd4557be503dce5dcbe7a03037bc5fe4efb29b11a62cd6549a745' 
  AND token = 'LGtuajZ0EwLwPGCR+WDH3xzvpUNnyiqJUCx9g0zky4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}