SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01df9bc08d173c3943d66e9b263d82f4520ecd7081aaf262900d6f6e5425ce96' 
  AND token = 'WQ7APX7WIEkodpS1EitUTReVidooqRexHzVbIjKLr0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}