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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2203e414ec23111aeabe9a021e7b251ec56f5b36f50e81d8fdf64e60d7df769c' 
  AND token = 'enaZ+Oz0H0+JFyJsPOaQi18E7glw/0F0UrVP0gF267c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}