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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f49de9c1abdce4db4a27fc680a1d8c667ab405a7330c2bc6c7d014d94b493c' 
  AND token = 'WBqGvYm8WvKOT1CjQ/Hpgpf1y/MZrXtiZP742713WSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}