SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53811637faffbf02635e013d0002c598669a47838ca5c11c55d7993f52184b49' 
  AND token = 'DS8d/L+JteW8Y0ffYUjbxV82aibacG2B4o3DW2iJYdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}