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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecca617ef77fd25a759c51c3f5f492f858d7be60899029e7622269d20a1e8e3c' 
  AND token = 'dIZ1c8Rc0OzahefJMTh6vKmsViqdrGA0XDP+pn/7NCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}