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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36a712e66439b53cad67be1658c672979b8bdcec4807330177d2fa06fbed904c' 
  AND token = 'RS0WopH2Wm2gPBDlNHEUfK106c9gp9z3UPkP86ux250=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}