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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f9da4a5390793ef15244ddb0cd8fa94b69a25235624edc7d7002f3b41fa522' 
  AND token = 'bO+JikT1ZEOkKZAcMbz5ny894kDfqR8VpgQtlBMRArk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}