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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b8e0d6d8d25890cbfddf9df9d3aaf0143d656f10d713f9ce95db19b142559b' 
  AND token = 'S6/+x1m+8LeOzpt64eNtiTQPQzLOrYUXvYewHHPm1hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}