SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37026d3bc20a4dadb8836437b7adf745d991758b743ef1c4482508d2b69c0172' 
  AND token = 'nEpRYq41LaMtYt26KA/JDs7xO24ZWw8MPiZIWuskhlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}