SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd9c5a2ba10c37175748b09ce4af464534530b56a381c319edd00accbd43d04' 
  AND token = 'D2pltyJJWdaAbE7M02WtW+6kQEVUR9jJ5m3VtSzMm4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}