SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074391d048cde53a33dc27a0d71760b21ca5e724bf257fe1f232fa9be70f02b9' 
  AND token = 'WfDlVvwtty3WwN9BTi4aRhH/hYfg1YDwScFPeFvhMYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}