SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc87b77f770a7994d536a2aa52f8a2dab11cc62477db457d78d362f0fa10476d' 
  AND token = 'EVW/ZVLM8jwu0h8q/CO30s+qSHWuPR9X/oAFhngp7c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}