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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34f88bf874f5998271ddbfc8cfac9215ea4ecb07f21c80329ad905068ea3cfe9' 
  AND token = 'v4iAXO5wtGxs/PVwNRb5IRUNhL/gElIv7CWOyGl+eR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}