SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508d26ac5af8ad669492fa75a3d5ba722ca2cf859bbdb9f10b05cad601b9c8f5' 
  AND token = 'tkG57cy0XDXXr7ASnhrPUBYCFp0v0ij9EmWzxqU7Tdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}