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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f37d5887e7d8701cc84387d3d67a9e184191716029f68b6032d1df52f2e709f' 
  AND token = 'XBsbo1NxIxfFyNbdBS8xQfGF4afiAfECEZI8z6R0cGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}