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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc295943ad9bee97edb677da5bbec9c2c6e14b4c945d3f04a8ec7573c22cb9b' 
  AND token = '6LzMLrH/QFuP9KCp+0+dgDrdbO9HG9sFVa4La35eSsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}