SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395e07e09039ae83d82fb8b2db6f69f31876201fcbf3343e7392eb421245f10c' 
  AND token = 'jOPbVW4js/+C0FUr/xqh8er/9GVUBKSV9sTBdc/WnpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}