SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c1037f449044fe0407cd9f880d44c20a2a92cb0cfe205a67cb4606df65ad89' 
  AND token = '/JO5YSDV/FRozmlnI5+c4P/0XQgLN9AN5Si5JZNdpH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}