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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89ca897cdd9033ef64e512846313dc43c4378797ccbcbc30b78f1fa248675ab' 
  AND token = '10npiqLuUj8PfIXVdq7nw2nN1iQOjD0LwCuwOeMXWqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}