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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336c0135546cea793754bad4496f18e3196efa70eb465373eb246ed523f654c1' 
  AND token = 'uMV9wx8E1UJcShHrI3bI54SQ7x0qTw3zUfAhes2hT/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}