SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a7e03f97833c7f6531945921011fd405eed2485ad9fb680201120324acdbcc' 
  AND token = 'RfTSJqlrEDZ0SN0nfZSWGQS6UHSqljc2n7OyyU5ElkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}