SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4b1c0f02e8274829d9c9b9371500fbc7bebf27ed7a122cf72cad20910dbf6b6' 
  AND token = 'ykRgT9y0q8yipJayhuqe3cIFSQ2WXmLF3IkBUqdA/PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}