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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d76082bb5cf2e665b46cbcea4a063a55dfdc2e01217931a3165332ba4c07f44' 
  AND token = 'UVr3J1zpuSV6vW4ZdDaR6PEX9GGoPsxQkbnufyk25E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}