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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e712bd12336f26c7c452c6024937236a52cacc050871ec63a2a72c131a3a588' 
  AND token = 'TVuA6JekJiepCES/SpBFDRU+cKxfDPplJbx4TrCR6dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}