SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b196463e674885aab2ed43b6cd81df40669d9a32d5c01b3070b0f357682792' 
  AND token = 'Cwu5htUbJF4MYmnSzDxs7FQUGDe5PCQtVZ6SJOTlLsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}