SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0c430735ea28481321a7b4ad072b5fdf22c478d3ae7624994979db548431d4' 
  AND token = 'tlFXJ6vYg4dQv/P7aYqSAlUGkZ1XfS+83II3fp+Mcjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}