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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b9b677f5470b8a9210764b70e0112f9533006198ef62ec1a91668500200507' 
  AND token = 's+PTIIrkwnbCoyPpujcdqpPC5lKTPLkvACOKB5m+yCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}