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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff47ed1079d07d3e65cf46ee26222a15bd30a7495774661ae5ed4293bfb8d4cc' 
  AND token = 'M4+tX/1ShkyL67yEGq4aXp4Lwh1aCp5R6WFAAOZPla8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}