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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f48ca8d9e7e14f9a3229d098500b7d51c1800a3049469118361b91b03fa81f4' 
  AND token = 'uSaionGdcSLDOEmt3ospu3snxlULhRv8buPh9+V2UMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}