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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d46c2f71ebf2f7e2fab6c77ba3be323b6aaa68f02420b324810b557ea76348d' 
  AND token = 'I0Kt1UQ67UTxw2peP1Z8e5dIH/ForkzpWxweQTsOMDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}