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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3fa16a55058289adc95287627e21329bddbe4181a8ec0281cfd2b56ea0e9632' 
  AND token = 'rZ+8a8fukY6Q1/tLFhCMgO/OAW01y74nUUVFNfhsFpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}