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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2607f9968c27ad0b75644a9283aadc0fcfa023500ff1d3ae51a6b0b375a8287' 
  AND token = 'NppY09K14clawE97H4izMWeaBuEIq1nLnbdGCPyrSRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}