SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195490f85cd218b9306705ac1d7bbcc29feb9ea146be858e6b22607471aaec4c' 
  AND token = 'iyTJpw8cHEtZFFZrVNsk77W6ctqoQovQNmSJW+/ytFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}