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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543de50f5dc2d8097bb27ed14723428d104d0f8925e52ffcd5c6ab7ed10d1b9b' 
  AND token = 'B6nMKiBxVfOSdtexZa1js3C9QBltp2wQNHMd1WYycKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}