SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1109961c74bdbf60b9a8d725164b2eda5c447803285ccffb675b867c8ecaef' 
  AND token = 'dcz4nts4/ea0SlQlZ7ropUOwwC9g28+UDPfexZ91i5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}