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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043064b5640113047959118a104732de6e41e3ccee01f502ff694e6e10b0a0bb' 
  AND token = 'lIHCJ2WpRFoZbNlnKFc3A5EC/Z2ICjLQOQWq0AN+9iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}