SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be0a2800d11629a9477d4e466be360815654c2c70ee0e6dd165208e2a74c41a' 
  AND token = 'nRruhKSiJCZfm7vEWu/it9tB3aEHUNmCC6WxuiFUvK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}