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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54756b1a661fd6a10d4b0cdd20a09de04488e0e1f33faa12f6e7cd7a25b3dd7f' 
  AND token = 'ERsOJQYYWGhF0IWjfZeC5rTROgU6V9vAkDuP3Xjm3/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}