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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133d823e529bd6593156adce34e4231706c6803f53fd61ee99f853d44fcc59b4' 
  AND token = 'T+7lIeyBURDH2w7wSYBmUzaXxNJ5B8T7MFvGXJyGpEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}