SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab452de642dd77cf94e398d2bbcc04cd3130768fa21022573a5f065a5fc7476c' 
  AND token = 'tdbFt19q790cB0vZoPFg4dc7kNJcTLfdzGtPJji7bFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}