SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e980e8d46aa158fccc71ef191fc9617eec7889f9f9bcc0609463aeb15f988700' 
  AND token = '/IZ9D9gLGl4u3nnyPKGPsxtQW1JgosQHZwAz7f5n0Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}