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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81e994744ab60ec3eae38498f4901419e5fbf45540017e98fb62feb4de2bfb8' 
  AND token = '2Aa1K1ItCugqe2Rlum8YS5xNrcHG+m2ps9Mzb/eYZQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}